Xerostomia Research Today is a free monthly online journal that collates and summarizes the latest research about Xerostomia, including details on dry mouth, treatment, causes, lack of saliva.

Interferon alfa treatment for Sjogren's syndrome associated neuropathy.

Yamada S, Mori K, Matsuo K, Inukai A, Kawagashira Y, Sobue G

Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa, Nagoya 466-8550, Japan.

Treatment response to interferon alfa (IFNalpha) is described in three consecutive cases of two forms of Sjogren's syndrome associated neuropathy (SSN)-two with sensory ataxic ganglionopathy and one with sensorimotor neuropathy with demyelinating features. All responded well to IFNalpha in terms of neuropathic symptoms, sicca symptoms, antibody titres, and findings in salivary gland biopsy specimens. IFNalpha thus showed promise in treating both SSN and the underlying Sjogren's syndrome.

Published 18 March 2005 in J Neurol Neurosurg Psychiatry, 76(4): 576-8.
Full-text of this article is available online (may require subscription).

© 2005-2008 Xerostomia Research Today. All Rights Reserved.