Xerostomia Research - Dry Mouth, Treatment, Causes, Lack of Saliva

Xerostomia Research Today is a free monthly online journal that collates and summarizes the latest research about Xerostomia, including details on dry mouth, treatment, causes, lack of saliva.


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A preliminary report on patient acceptance of a novel intra-oral lubricating device for the management of radiotherapy-related xerostomia.

Kam AY, McMillan AS, Pow EH, Leung KC, Luk HW

Faculty of Dentistry, University of Hong Kong, 34 Hospital Road, Hong Kong.

Management of radiotherapy-related xerostomia is difficult. Saliva substitutes are helpful but the effects are short-lived. The purpose of the study was to develop a prototype intra-oral lubricating device for the management of radiotherapy-related xerostomia and to evaluate patient acceptance. An intra-oral lubricating device was fabricated that incorporated a reservoir in the palatal vault and permitted slow release of saliva substitute by the patient. Preliminary clinical testing was done in five patients with radiotherapy-related xerostomia. A measure incorporating seven questions was used to explore patient acceptance. The device was simple to fabricate using materials available in a technical laboratory. All patients were able to wear the device for at least 4 h per day throughout the test period. The device was considered easy to use and clean. Some impairment of speech and chewing was noted although this appeared to be related to the bulkiness of the reservoir. General oral comfort was improved due to the lubricating effect. The bulk of the reservoir was reduced as a consequence of patient feedback. The design addressed key problems associated with previous lubricating systems. Patient reports on oral functioning with the device in situ provided pivotal information on the device's utility.

Published 31 August 2005 in Clin Oral Investig, 9(3): 148-53.
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Xerostomia Research Today Archive:

Volume 1 (2005)
  Issue 1 (March)
  Issue 2 (April)
  Issue 3 (May)
  Issue 4 (June)
  Issue 5 (July)
  Issue 6 (August)
  Issue 7 (September)
  Issue 8 (October)
  Issue 9 (November)
  Issue 10 (December)

Volume 2 (2006)
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Volume 3 (2007)
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  Issue 10 (October)
  Issue 11 (November)
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Volume 4 (2008)
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  Issue 6 (June)
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  Issue 8 (August)



Xerostomia Books

The I-Can't-Chew Cookbook: Delicious Soft Diet Recipes for People with Chewing, Swallowing, and Dry Mouth Disorders

The I-Can't-Chew Cookbook: Delicious Soft Diet Recipes for People with Chewing, Swallowing, and Dry Mouth Disorders