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Life-threatening acute pulmonary haemorrhage in primary Sjögren's syndrome with cryoglobulinaemia.

Johnston SL, Dudley CR, Unsworth DJ, Lock RJ

Department of Immunology, North Bristol NHS Trust, Southmead Hospital, Bristol, UK. Sarah.Johnston@nbt.nhs.uk

We describe a woman with primary Sjögren's syndrome who presented with an acute pulmonary-renal syndrome resulting from cryoglobulinaemic vasculitis. Pulmonary manifestations of Sjögren's syndrome are relatively common, whereas overt pulmonary complications of cryoglobulinaemia are rare. Pulmonary haemorrhage is rare in either disorder. The combination of Sjögren's syndrome, cryoglobulinaemia, and acute pulmonary haemorrhage has not been previously reported.

Published 19 October 2005 in Scand J Rheumatol, 34(5): 404-7.
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